Cross-Comparison of Exome Analysis, Next-Generation Sequencing of Amplicons, and the iPLEX(®) ADME PGx Panel for Pharmacogenomic Profiling

Whole-exome sequencing (WES) has been widely used for analysis of human genetic diseases, but its value for the pharmacogenomic profiling of individuals is not well studied. Initially, we performed an in-depth evaluation of the accuracy of WES variant calling in the pharmacogenes CYP2D6 and CYP2C19...

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Detalles Bibliográficos
Autores principales: Chua, Eng Wee, Cree, Simone L., Ton, Kim N. T., Lehnert, Klaus, Shepherd, Phillip, Helsby, Nuala, Kennedy, Martin A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4726781/
https://www.ncbi.nlm.nih.gov/pubmed/26858644
http://dx.doi.org/10.3389/fphar.2016.00001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4726781/
https://www.ncbi.nlm.nih.gov/pubmed/26858644
http://dx.doi.org/10.3389/fphar.2016.00001

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