Chaperonin GroEL/GroES Over-Expression Promotes Aminoglycoside Resistance and Reduces Drug Susceptibilities in Escherichia coli Following Exposure to Sublethal Aminoglycoside Doses

Antibiotic resistance is an increasing challenge to modern healthcare. Aminoglycoside antibiotics cause translation corruption and protein misfolding and aggregation in Escherichia coli. We previously showed that chaperonin GroEL/GroES depletion and over-expression sensitize and promote short-term t...

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Detalles Bibliográficos
Autores principales: Goltermann, Lise, Sarusie, Menachem V., Bentin, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4726795/
https://www.ncbi.nlm.nih.gov/pubmed/26858694
http://dx.doi.org/10.3389/fmicb.2015.01572

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4726795/
https://www.ncbi.nlm.nih.gov/pubmed/26858694
http://dx.doi.org/10.3389/fmicb.2015.01572

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