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A Computational Model for the AMPA Receptor Phosphorylation Master Switch Regulating Cerebellar Long-Term Depression

The expression of long-term depression (LTD) in cerebellar Purkinje cells results from the internalisation of α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptors (AMPARs) from the postsynaptic membrane. This process is regulated by a complex signalling pathway involving sustained protein...

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Detalles Bibliográficos
Autores principales: Gallimore, Andrew R., Aricescu, A. Radu, Yuzaki, Michisuke, Calinescu, Radu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4726815/
https://www.ncbi.nlm.nih.gov/pubmed/26807999
http://dx.doi.org/10.1371/journal.pcbi.1004664