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A Computational Model for the AMPA Receptor Phosphorylation Master Switch Regulating Cerebellar Long-Term Depression
The expression of long-term depression (LTD) in cerebellar Purkinje cells results from the internalisation of α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptors (AMPARs) from the postsynaptic membrane. This process is regulated by a complex signalling pathway involving sustained protein...
Autores principales: | Gallimore, Andrew R., Aricescu, A. Radu, Yuzaki, Michisuke, Calinescu, Radu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4726815/ https://www.ncbi.nlm.nih.gov/pubmed/26807999 http://dx.doi.org/10.1371/journal.pcbi.1004664 |
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