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The Inflammasome and the Epidermal Growth Factor Receptor (EGFR) Are Involved in the Staphylococcus aureus-Mediated Induction of IL-1alpha and IL-1beta in Human Keratinocytes

Staphylococcus (S.) aureus is an important pathogen causing various infections including those of the skin. Keratinocytes are able to sense invading S. aureus and to initiate a fast defense reaction by the rapid release of innate defense mediators such as antimicrobial peptides and cytokines. There...

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Detalles Bibliográficos
Autores principales: Simanski, Maren, Rademacher, Franziska, Schröder, Lena, Gläser, Regine, Harder, Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4726826/
https://www.ncbi.nlm.nih.gov/pubmed/26808616
http://dx.doi.org/10.1371/journal.pone.0147118