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Loss of epidermal growth factor receptor expression in oral squamous cell carcinoma is associated with invasiveness and epithelial-mesenchymal transition

Inhibition of epidermal growth factor receptor (EGFR) signaling has emerged as a novel therapeutic strategy for the treatment of oral squamous cell carcinoma (OSCC). The EGFR-directed inhibitor cetuximab is currently the only approved targeted therapy for the treatment of OSCC. EGFR status may affec...

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Detalles Bibliográficos
Autores principales: KIMURA, IYO, KITAHARA, HIROKO, OOI, KAZUHIRO, KATO, KOROKU, NOGUCHI, NATUYO, YOSHIZAWA, KUNIO, NAKAMURA, HIROYUKI, KAWASHIRI, SHUICHI
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4727181/
https://www.ncbi.nlm.nih.gov/pubmed/26870189
http://dx.doi.org/10.3892/ol.2015.3833