Integrin β1-mediated acquired gefitinib resistance in non-small cell lung cancer cells occurs via the phosphoinositide 3-kinase-dependent pathway

The present study aimed to explore the role of integrin β1 and the relevant signaling pathways in acquired gefitinib resistance in non-small cell lung cancer (NSCLC). The inhibitory effects of gefitinib, with or without LY294002, on cellular proliferation were evaluated by 3-(4,5-dimethylthiazol-2-y...

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Detalles Bibliográficos
Autores principales: DENG, QIN-FANG, SU, BO, ZHAO, YIN-MIN, TANG, LIANG, ZHANG, JIE, ZHOU, CAI-CUN
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4727211/
https://www.ncbi.nlm.nih.gov/pubmed/26870244
http://dx.doi.org/10.3892/ol.2015.3945

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4727211/
https://www.ncbi.nlm.nih.gov/pubmed/26870244
http://dx.doi.org/10.3892/ol.2015.3945

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