Regulation of miR-200c/141 expression by intergenic DNA-looping and transcriptional read-through

The miR-200 family members have been implicated in stress responses and ovarian tumorigenesis. Here, we find that miR-200c/141 transcription is intimately linked to the transcription of the proximal upstream gene PTPN6 (SHP1) in all physiological conditions tested. PTPN6 and miR-200c/141 are transcr...

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Detalles Bibliográficos
Autores principales: Batista, Luciana, Bourachot, Brigitte, Mateescu, Bogdan, Reyal, Fabien, Mechta-Grigoriou, Fatima
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4727242/
https://www.ncbi.nlm.nih.gov/pubmed/26725650
http://dx.doi.org/10.1038/ncomms9959

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4727242/
https://www.ncbi.nlm.nih.gov/pubmed/26725650
http://dx.doi.org/10.1038/ncomms9959

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