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Expression, purification and biological characterization of the extracellular domain of CD40 from Pichia pastoris
BACKGROUND: CD40, also called Bp50, is a novel member of the TNF receptor superfamily. Based on its important role in multiple physiological and pathological processes, the CD40 signaling pathway has become a vital target for treating transplantation, autoimmune diseases and cancers. This study gene...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4727258/ https://www.ncbi.nlm.nih.gov/pubmed/26809818 http://dx.doi.org/10.1186/s12896-016-0237-1 |