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Expression, purification and biological characterization of the extracellular domain of CD40 from Pichia pastoris

BACKGROUND: CD40, also called Bp50, is a novel member of the TNF receptor superfamily. Based on its important role in multiple physiological and pathological processes, the CD40 signaling pathway has become a vital target for treating transplantation, autoimmune diseases and cancers. This study gene...

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Detalles Bibliográficos
Autores principales: Zhan, Yu, Wei, Yilei, Chen, Pengfei, Zhang, Haohao, Liu, Dandan, Zhang, Jie, Liu, Rongzeng, Chen, Ran, Zhang, Jun, Mo, Wei, Zhang, Xiaoren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4727258/
https://www.ncbi.nlm.nih.gov/pubmed/26809818
http://dx.doi.org/10.1186/s12896-016-0237-1