A pivot mutation impedes reverse evolution across an adaptive landscape for drug resistance in Plasmodium vivax

BACKGROUND: The study of reverse evolution from resistant to susceptible phenotypes can reveal constraints on biological evolution, a topic for which evolutionary theory has relatively few general principles. The public health catastrophe of antimicrobial resistance in malaria has brought these cons...

Descripción completa

Detalles Bibliográficos
Autores principales: Ogbunugafor, C. Brandon, Hartl, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4727274/
https://www.ncbi.nlm.nih.gov/pubmed/26809718
http://dx.doi.org/10.1186/s12936-016-1090-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4727274/
https://www.ncbi.nlm.nih.gov/pubmed/26809718
http://dx.doi.org/10.1186/s12936-016-1090-3

Ejemplares similares