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The binding specificity of Translocated in LipoSarcoma/FUsed in Sarcoma with lncRNA transcribed from the promoter region of cyclin D1

BACKGROUND: Translocated in LipoSarcoma (TLS, also known as FUsed in Sarcoma) is an RNA/DNA binding protein whose mutation cause amyotrophic lateral sclerosis. In previous study, we demonstrated that TLS binds to long noncoding RNA, promoter-associated ncRNA-D (pncRNA-D), transcribed from the 5′ ups...

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Detalles Bibliográficos
Autores principales: Yoneda, Ryoma, Suzuki, Shiho, Mashima, Tsukasa, Kondo, Keiko, Nagata, Takashi, Katahira, Masato, Kurokawa, Riki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4727290/
https://www.ncbi.nlm.nih.gov/pubmed/26816614
http://dx.doi.org/10.1186/s13578-016-0068-8