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Loss of nuclear localization of TET2 in colorectal cancer

5-Hydroxymethylcytosine (5hmC) is lost in multiple human cancers, including colorectal cancer (CRC). Decreased ten-eleven translocation 1 (TET1) messenger RNA (mRNA), but not other two TET family members, has been observed in the colorectal cancer and is crucial for colorectal cancer initiation. Her...

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Detalles Bibliográficos
Autores principales: Huang, Yuji, Wang, Guanghui, Liang, Zhonglin, Yang, Yili, Cui, Long, Liu, Chen-Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4727298/
https://www.ncbi.nlm.nih.gov/pubmed/26816554
http://dx.doi.org/10.1186/s13148-016-0176-7