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Knockdown of CLIC4 enhances ATP-induced HN4 cell apoptosis through mitochondrial and endoplasmic reticulum pathways

BACKGROUND: Human head and neck squamous carcinoma is the 6th most prevalent carcinoma worldwide. Although many novel therapies have been developed, the clinical treatment for patients remains non-ideal. Chloride intracellular channel 4 (CLIC4), one of the seven members of the CLIC family, is a newl...

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Detalles Bibliográficos
Autores principales: Xue, Haowei, Lu, Jinsen, Yuan, Renxiang, Liu, Jinli, Liu, Yehai, Wu, Kaile, Wu, Jing, Du, Juan, Shen, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4727302/
https://www.ncbi.nlm.nih.gov/pubmed/26816615
http://dx.doi.org/10.1186/s13578-016-0070-1