LINE-1 silencing by retinoblastoma proteins is effected through the nucleosomal and remodeling deacetylase multiprotein complex

BACKGROUND: Long Interspersed Nuclear Element-1 (L1) is an oncogenic mammalian retroelement silenced early in development via tightly controlled epigenetic mechanisms. We have previously shown that the regulatory region of human and murine L1s interact with retinoblastoma (RB) proteins to effect ret...

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Detalles Bibliográficos
Autores principales: Montoya-Durango, Diego E., Ramos, Kenneth A., Bojang, Pasano, Ruiz, Lorell, Ramos, Irma N., Ramos, Kenneth S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4727354/
https://www.ncbi.nlm.nih.gov/pubmed/26810492
http://dx.doi.org/10.1186/s12885-016-2068-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4727354/
https://www.ncbi.nlm.nih.gov/pubmed/26810492
http://dx.doi.org/10.1186/s12885-016-2068-9

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