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Killer-cell Immunoglobulin-like Receptor (KIR) gene profiles modify HIV disease course, not HIV acquisition in South African women

BACKGROUND: Killer-cell Immunoglobulin-like Receptors(KIR) interact with Human Leukocyte Antigen(HLA) to modify natural killer- and T-cell function. KIR are implicated in HIV acquisition by small studies that have not been widely replicated. A role for KIR in HIV disease progression is more widely r...

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Detalles Bibliográficos
Autores principales: Naranbhai, V., de Assis Rosa, D., Werner, L., Moodley, R., Hong, H., Kharsany, A., Mlisana, K., Sibeko, S., Garrett, N., Chopera, D., Carr, W. H., Abdool Karim, Q., Hill, A. V. S., Abdool Karim, S. S., Altfeld, M., Gray, C. M., Ndung’u, T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4727384/
https://www.ncbi.nlm.nih.gov/pubmed/26809736
http://dx.doi.org/10.1186/s12879-016-1361-1