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Epigenetic Regulation of Tissue-Type Plasminogen Activator in Human Brain Tissue and Brain-Derived Cells

The serine protease tissue-type plasminogen activator (t-PA) is involved in both vital physiological brain processes, such as synaptic plasticity, and pathophysiological conditions, such as neurodegeneration and ischemic stroke. Recent data suggest that epigenetic mechanisms play an important role i...

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Detalles Bibliográficos
Autores principales: Olsson, Martina, Hultman, Karin, Dunoyer-Geindre, Sylvie, Curtis, Maurice A., Faull, Richard L. M., Kruithof, Egbert K. O., Jern, Christina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Libertas Academica 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4727487/
https://www.ncbi.nlm.nih.gov/pubmed/26823649
http://dx.doi.org/10.4137/GRSB.S30241