Extended Release of an Anti–Heparan Sulfate Peptide From a Contact Lens Suppresses Corneal Herpes Simplex Virus-1 Infection

PURPOSE: To prolong the release of a heparan sulfate binding peptide, G2-C, using a commercially available contact lens as a delivery vehicle and to demonstrate the ability of the released peptide to block herpes simplex virus-1 (HSV-1) infection using in vitro, ex vivo, and in vivo models of cornea...

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Detalles Bibliográficos
Autores principales: Jaishankar, Dinesh, Buhrman, Jason S., Valyi-Nagy, Tibor, Gemeinhart, Richard A., Shukla, Deepak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2016
Materias:
Immunology and Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4727529/
https://www.ncbi.nlm.nih.gov/pubmed/26780322
http://dx.doi.org/10.1167/iovs.15-18365

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4727529/
https://www.ncbi.nlm.nih.gov/pubmed/26780322
http://dx.doi.org/10.1167/iovs.15-18365

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