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Extended Release of an Anti–Heparan Sulfate Peptide From a Contact Lens Suppresses Corneal Herpes Simplex Virus-1 Infection
PURPOSE: To prolong the release of a heparan sulfate binding peptide, G2-C, using a commercially available contact lens as a delivery vehicle and to demonstrate the ability of the released peptide to block herpes simplex virus-1 (HSV-1) infection using in vitro, ex vivo, and in vivo models of cornea...
Autores principales: | Jaishankar, Dinesh, Buhrman, Jason S., Valyi-Nagy, Tibor, Gemeinhart, Richard A., Shukla, Deepak |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Association for Research in Vision and Ophthalmology
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4727529/ https://www.ncbi.nlm.nih.gov/pubmed/26780322 http://dx.doi.org/10.1167/iovs.15-18365 |
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