Imiquimod‐induced apoptosis of melanoma cells is mediated by ER stress‐dependent Noxa induction and enhanced by NF‐κB inhibition

Melanoma is characterized by dysregulated intracellular signalling pathways including an impairment of the cell death machinery, ultimately resulting in melanoma resistance, survival and progression. This explains the tumour's extraordinary resistance to the standard treatment. Imiquimod is a t...

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Detalles Bibliográficos
Autores principales: El‐Khattouti, Abdelouahid, Selimovic, Denis, Hannig, Matthias, Taylor, Erin B., Abd Elmageed, Zakaria Y., Hassan, Sofie Y., Haikel, Youssef, Kandil, Emad, Leverkus, Martin, Brodell, Robert T., Megahed, Mosaad, Hassan, Mohamed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4727561/
https://www.ncbi.nlm.nih.gov/pubmed/26578344
http://dx.doi.org/10.1111/jcmm.12718

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4727561/
https://www.ncbi.nlm.nih.gov/pubmed/26578344
http://dx.doi.org/10.1111/jcmm.12718

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