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β cell membrane remodelling and procoagulant events occur in inflammation‐driven insulin impairment: a GLP‐1 receptor dependent and independent control

Inflammation and hyperglycaemia are associated with a prothrombotic state. Cell‐derived microparticles (MPs) are the conveyors of active procoagulant tissue factor (TF) and circulate at high concentration in diabetic patients. Liraglutide, a glucagon‐like peptide (GLP)‐1 analogue, is known to promot...

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Detalles Bibliográficos
Autores principales: Gleizes, Céline, Kreutter, Guillaume, Abbas, Malak, Kassem, Mohamad, Constantinescu, Andrei Alexandru, Boisramé‐Helms, Julie, Yver, Blandine, Toti, Florence, Kessler, Laurence
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4727568/
https://www.ncbi.nlm.nih.gov/pubmed/26607759
http://dx.doi.org/10.1111/jcmm.12683