A Rapid, Cost-Effective Pre-Clinical Method to Screen for Pro- or Antiarrhythmic Effects of Substances in an Isolated Heart Preparation

This study describes a rapid, cost-effective pre-clinical method to screen for pro- or antiarrhythmic effects of substances in an isolated heart preparation in line with the regulatory requirements of ICHS7B. The computational method “MFC method” quantifies arrhythmic episodes from isolated perfused...

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Detalles Bibliográficos
Autor principal: Borg, John Joseph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Austrian Journal of Pharmaceutical Sciences 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4727768/
https://www.ncbi.nlm.nih.gov/pubmed/26839822
http://dx.doi.org/10.3797/scipharm.1503-03

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4727768/
https://www.ncbi.nlm.nih.gov/pubmed/26839822
http://dx.doi.org/10.3797/scipharm.1503-03

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