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A Rapid, Cost-Effective Pre-Clinical Method to Screen for Pro- or Antiarrhythmic Effects of Substances in an Isolated Heart Preparation
This study describes a rapid, cost-effective pre-clinical method to screen for pro- or antiarrhythmic effects of substances in an isolated heart preparation in line with the regulatory requirements of ICHS7B. The computational method “MFC method” quantifies arrhythmic episodes from isolated perfused...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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The Austrian Journal of Pharmaceutical Sciences
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4727768/ https://www.ncbi.nlm.nih.gov/pubmed/26839822 http://dx.doi.org/10.3797/scipharm.1503-03 |