A hyperbranched dopamine-containing PEG-based polymer for the inhibition of α-synuclein fibrillation

Aggregation of α-synuclein is believed to play an important role in Parkinson's disease and in other neurodegenerative maladies. Small molecule inhibitors of this process are among the most promising drug candidates for neurodegenerative diseases. Dendrimers have also been studied for anti-fibr...

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Detalles Bibliográficos
Autores principales: Breydo, Leonid, Newland, Ben, Zhang, Hong, Rosser, Anne, Werner, Carsten, Uversky, Vladimir N., Wang, Wenxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4727786/
https://www.ncbi.nlm.nih.gov/pubmed/26707645
http://dx.doi.org/10.1016/j.bbrc.2015.12.060

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4727786/
https://www.ncbi.nlm.nih.gov/pubmed/26707645
http://dx.doi.org/10.1016/j.bbrc.2015.12.060

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