Cargando…
A hyperbranched dopamine-containing PEG-based polymer for the inhibition of α-synuclein fibrillation
Aggregation of α-synuclein is believed to play an important role in Parkinson's disease and in other neurodegenerative maladies. Small molecule inhibitors of this process are among the most promising drug candidates for neurodegenerative diseases. Dendrimers have also been studied for anti-fibr...
Autores principales: | Breydo, Leonid, Newland, Ben, Zhang, Hong, Rosser, Anne, Werner, Carsten, Uversky, Vladimir N., Wang, Wenxin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Academic Press
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4727786/ https://www.ncbi.nlm.nih.gov/pubmed/26707645 http://dx.doi.org/10.1016/j.bbrc.2015.12.060 |
Ejemplares similares
-
The Impact of Polymer Size and Cleavability on the Intravenous Pharmacokinetics of PEG-Based Hyperbranched Polymers in Rats
por: Marasini, Nirmal, et al.
Publicado: (2020) -
α-Synuclein Fibrils as Penrose Machines: A Chameleon in the Gear
por: De Giorgi, Francesca, et al.
Publicado: (2022) -
Effects of Various Flavonoids on the α-Synuclein Fibrillation Process
por: Meng, Xiaoyun, et al.
Publicado: (2010) -
Thermoresponsive and Reducible Hyperbranched Polymers Synthesized by RAFT Polymerisation
por: Tochwin, Anna, et al.
Publicado: (2017) -
In situ Forming Hyperbranched PEG—Thiolated Hyaluronic Acid Hydrogels With Honey-Mimetic Antibacterial Properties
por: Vasquez, Jeddah Marie, et al.
Publicado: (2021)