Cost-Effective Isolation of a Process Impurity of Pregabalin

Cost-effective isolation methods were developed on preparative HPLC, flash LC, and simulated moving bed (SMB) to prepare the process impurity, 3-(aminomethyl)-5-methylhex-4-enoic acid (4-ene impurity), of pregabalin. By a thorough experimental study on the different isolation techniques available, i...

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Detalles Bibliográficos
Autores principales: Prakash, Lakkireddy, Himaja, Malipeddi, Ramakrishna Yadav, Belly, Maheshwara Reddy, Arumalla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Austrian Journal of Pharmaceutical Sciences 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4727790/
https://www.ncbi.nlm.nih.gov/pubmed/26839830
http://dx.doi.org/10.3797/scipharm.1501-16

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4727790/
https://www.ncbi.nlm.nih.gov/pubmed/26839830
http://dx.doi.org/10.3797/scipharm.1501-16

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