Identification, Isolation, and Characterization of a New Degradation Impurity in Nafcillin Sodium

A new degradant of Nafcillin Sodium was found at a level of 1.8% w/w during the gradient reversed-phase HPLC analysis in stability storage samples. This impurity was identified by LC-MS and was characterized by (1)H-NMR, (13)C-NMR, LC/MS/MS, elemental analysis, and IR techniques. Based on the struct...

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Detalles Bibliográficos
Autores principales: Vundavilli, Jagadeesh Kumar, Kothapalli, Pavan Kumar S. R., Peruri, Badarinadh Gupta, Korrapati, Prasada Rao V. V., Sharma, Hemant Kumar, Nallapati, Sreenivas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Austrian Journal of Pharmaceutical Sciences 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4727811/
https://www.ncbi.nlm.nih.gov/pubmed/26839804
http://dx.doi.org/10.3797/scipharm.1408-03

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4727811/
https://www.ncbi.nlm.nih.gov/pubmed/26839804
http://dx.doi.org/10.3797/scipharm.1408-03

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