Genetic Variation, Not Cell Type of Origin, Underlies the Majority of Identifiable Regulatory Differences in iPSCs

The advent of induced pluripotent stem cells (iPSCs) revolutionized human genetics by allowing us to generate pluripotent cells from easily accessible somatic tissues. This technology can have immense implications for regenerative medicine, but iPSCs also represent a paradigm shift in the study of c...

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Detalles Bibliográficos
Autores principales: Burrows, Courtney K., Banovich, Nicholas E., Pavlovic, Bryan J., Patterson, Kristen, Gallego Romero, Irene, Pritchard, Jonathan K., Gilad, Yoav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4727884/
https://www.ncbi.nlm.nih.gov/pubmed/26812582
http://dx.doi.org/10.1371/journal.pgen.1005793

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4727884/
https://www.ncbi.nlm.nih.gov/pubmed/26812582
http://dx.doi.org/10.1371/journal.pgen.1005793

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