Serine Metabolism Supports the Methionine Cycle and DNA/RNA Methylation through De Novo ATP Synthesis in Cancer Cells

Crosstalk between cellular metabolism and the epigenome regulates epigenetic and metabolic homeostasis and normal cell behavior. Changes in cancer cell metabolism can directly impact epigenetic regulation and promote transformation. Here we analyzed the contribution of methionine and serine metaboli...

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Detalles Bibliográficos
Autores principales: Maddocks, Oliver D.K., Labuschagne, Christiaan F., Adams, Peter D., Vousden, Karen H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4728077/
https://www.ncbi.nlm.nih.gov/pubmed/26774282
http://dx.doi.org/10.1016/j.molcel.2015.12.014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4728077/
https://www.ncbi.nlm.nih.gov/pubmed/26774282
http://dx.doi.org/10.1016/j.molcel.2015.12.014

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