Two-subunit DNA escort mechanism and inactive subunit bypass in an ultra-fast ring ATPase

SpoIIIE is a homo-hexameric dsDNA translocase responsible for completing chromosome segregation in Bacillus subtilis. Here, we use a single-molecule approach to monitor SpoIIIE translocation when challenged with neutral-backbone DNA and non-hydrolyzable ATP analogs. We show that SpoIIIE makes multip...

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Detalles Bibliográficos
Autores principales: Liu, Ninning, Chistol, Gheorghe, Bustamante, Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2015
Materias:
Biophysics and Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4728128/
https://www.ncbi.nlm.nih.gov/pubmed/26452092
http://dx.doi.org/10.7554/eLife.09224

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4728128/
https://www.ncbi.nlm.nih.gov/pubmed/26452092
http://dx.doi.org/10.7554/eLife.09224

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