Dissecting cancer evolution at the macro-heterogeneity and micro-heterogeneity scale

Intratumour heterogeneity complicates biomarker discovery and treatment personalization, and pervasive cancer evolution is a key mechanism leading to therapy failure and patient death. Thus, understanding subclonal heterogeneity architectures and cancer evolution processes is critical for the develo...

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Detalles Bibliográficos
Autores principales: Barber, Louise J, Davies, Matthew N, Gerlinger, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4728189/
https://www.ncbi.nlm.nih.gov/pubmed/25555261
http://dx.doi.org/10.1016/j.gde.2014.12.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4728189/
https://www.ncbi.nlm.nih.gov/pubmed/25555261
http://dx.doi.org/10.1016/j.gde.2014.12.001

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