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Dissecting cancer evolution at the macro-heterogeneity and micro-heterogeneity scale
Intratumour heterogeneity complicates biomarker discovery and treatment personalization, and pervasive cancer evolution is a key mechanism leading to therapy failure and patient death. Thus, understanding subclonal heterogeneity architectures and cancer evolution processes is critical for the develo...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4728189/ https://www.ncbi.nlm.nih.gov/pubmed/25555261 http://dx.doi.org/10.1016/j.gde.2014.12.001 |