Cargando…

PTP1B triggers integrin-mediated repression of myosin activity and modulates cell contractility

Cell contractility and migration by integrins depends on precise regulation of protein tyrosine kinase and Rho-family GTPase activities in specific spatiotemporal patterns. Here we show that protein tyrosine phosphatase PTP1B cooperates with β3 integrin to activate the Src/FAK signalling pathway whi...

Descripción completa

Detalles Bibliográficos
Autores principales:	González Wusener, Ana E., González, Ángela, Nakamura, Fumihiko, Arregui, Carlos O.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Company of Biologists Ltd 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4728310/ https://www.ncbi.nlm.nih.gov/pubmed/26700725 http://dx.doi.org/10.1242/bio.015883

Ejemplares similares

ER-Bound Protein Tyrosine Phosphatase PTP1B Interacts with Src at the Plasma Membrane/Substrate Interface
por: Monteleone, Melisa C., et al.
Publicado: (2012)

Impaired Integrin-mediated Adhesion and Signaling in Fibroblasts Expressing a Dominant-negative Mutant PTP1B
por: Arregui, Carlos O., et al.
Publicado: (1998)

P120-Catenin Regulates Early Trafficking Stages of the N-Cadherin Precursor Complex
por: Wehrendt, Diana P., et al.
Publicado: (2016)

PTP-1B is an essential positive regulator of platelet integrin signaling
por: Arias-Salgado, Elena Garcia, et al.
Publicado: (2005)

Myosin-X and talin modulate integrin activity at filopodia tips
por: Miihkinen, Mitro, et al.
Publicado: (2021)

The Protein Tyrosine Phosphatase PTP1B Is Required for Efficient Delivery of N-Cadherin to the Cell Surface
por: Hernández, Mariana V., et al.
Publicado: (2010)

Myosin turnover controls actomyosin contractile instability
por: Thiyagarajan, Sathish, et al.
Publicado: (2022)

Protein Tyrosine Phosphatase PTP1B Is Involved in Hippocampal Synapse Formation and Learning
por: Fuentes, Federico, et al.
Publicado: (2012)

The Nonreceptor Protein Tyrosine Phosphatase PTP1B Binds to the Cytoplasmic Domain of N-Cadherin and Regulates the Cadherin–Actin Linkage
por: Balsamo, Janne, et al.
Publicado: (1998)

Omecamtiv mercabil and blebbistatin modulate cardiac contractility by perturbing the regulatory state of the myosin filament
por: Kampourakis, Thomas, et al.
Publicado: (2017)

Myosin IIA-related Actomyosin Contractility Mediates Oxidative Stress-induced Neuronal Apoptosis
por: Wang, Yan, et al.
Publicado: (2017)

MCAK-mediated regulation of endothelial cell microtubule dynamics is mechanosensitive to myosin-II contractility
por: D’Angelo, Lauren, et al.
Publicado: (2017)

Cardiac myosin regulatory light chain kinase modulates cardiac contractility by phosphorylating both myosin regulatory light chain and troponin I
por: Sevrieva, Ivanka R., et al.
Publicado: (2020)

Modulation of myosin by cardiac myosin binding protein-C peptides improves cardiac contractility in ex-vivo experimental heart failure models
por: Hou, Luqia, et al.
Publicado: (2022)

Inhibition of PTP1B Restores IRS1-Mediated Hepatic Insulin Signaling in IRS2-Deficient Mice
por: González-Rodríguez, Águeda, et al.
Publicado: (2010)

Functions of Nonmuscle Myosin II in Assembly of the Cellular Contractile System
por: Shutova, Maria, et al.
Publicado: (2012)

ETS proto-oncogene 1 modulates PTP1B expression to participate in high glucose-mediated endothelial inflammation: Ets1 modulates PTP1B expression to participate in inflammation
por: Jiang, Lili, et al.
Publicado: (2022)

PTPα regulates integrin-stimulated FAK autophosphorylation and cytoskeletal rearrangement in cell spreading and migration
por: Zeng, Li, et al.
Publicado: (2003)

Myosin light chain kinase-driven myosin II turnover regulates actin cortex contractility during mitosis
por: Taneja, Nilay, et al.
Publicado: (2021)

The Nonreceptor Tyrosine Kinase Fer Mediates Cross-Talk between N-Cadherin and β1-Integrins
por: Arregui, Carlos, et al.
Publicado: (2000)

Interplay between myosin IIA-mediated contractility and actin network integrity orchestrates podosome composition and oscillations
por: van den Dries, K., et al.
Publicado: (2013)

Association of calmodulin and an unconventional myosin with the contractile vacuole complex of Dictyostelium discoideum
Publicado: (1992)

Interconversion of structural and contractile actin gels by insertion of myosin during assembly
Publicado: (1983)

Ultraslow Myosin Molecular Motors of Placental Contractile Stem Villi in Humans
por: Lecarpentier, Yves, et al.
Publicado: (2014)

PTP1B: mediating ROS signaling to silence genes
por: Boivin, Benoit, et al.
Publicado: (2015)

Mechanisms of PTPσ-Mediated Presynaptic Differentiation
por: Bomkamp, Claire, et al.
Publicado: (2019)

Myosin Isoforms and Contractile Properties of Single Fibers of Human Latissimus Dorsi Muscle
por: Paoli, Antonio, et al.
Publicado: (2013)

Myosin-driven actin-microtubule networks exhibit self-organized contractile dynamics
por: Lee, Gloria, et al.
Publicado: (2021)

Lumican Accelerates Wound Healing by Enhancing α2β1 Integrin-Mediated Fibroblast Contractility
por: Liu, Xiao-Jin, et al.
Publicado: (2013)

Pioglitazone Modulates the Vascular Contractility in Hypertension by Interference with ET-1 Pathway
por: Palacios-Ramírez, Roberto, et al.
Publicado: (2019)

Increased Protein Tyrosine Phosphatase 1B (PTP1B) Activity and Cardiac Insulin Resistance Precede Mitochondrial and Contractile Dysfunction in Pressure‐Overloaded Hearts
por: Nguyen, T. Dung, et al.
Publicado: (2018)

Spatial pattern of myosin phosphorylation in contracting smooth muscle cells: evidence for contractile zones
Publicado: (1988)

Myosin II dynamics and cortical flow during contractile ring formation in Dictyostelium cells
por: Yumura, Shigehiko
Publicado: (2001)

Dynamic myosin phosphorylation regulates contractile pulses and tissue integrity during epithelial morphogenesis
por: Vasquez, Claudia G., et al.
Publicado: (2014)

Substrate stiffness regulates cadherin-dependent collective migration through myosin-II contractility
por: Ng, Mei Rosa, et al.
Publicado: (2012)

Contractile acto-myosin network on nuclear envelope remnants positions human chromosomes for mitosis
por: Booth, Alexander JR, et al.
Publicado: (2019)

Nonmuscle myosin-2 contractility-dependent actin turnover limits the length of epithelial microvilli
por: Chinowsky, Colbie R., et al.
Publicado: (2020)

EMD-57033 Augments the Contractility in Porcine Myocardium by Promoting the Activation of Myosin in Thick Filaments
por: Jani, Vivek, et al.
Publicado: (2022)

Expression of Normally Repressed Myosin Heavy Chain 7b in the Mammalian Heart Induces Dilated Cardiomyopathy
por: Peter, Angela K., et al.
Publicado: (2019)

α-Glucosidase and PTP-1B Inhibitors from Malbranchea dendritica
por: Rebollar-Ramos, Daniela, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_4ct05544ikv019cg7j5v6ef2tp