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PTP1B triggers integrin-mediated repression of myosin activity and modulates cell contractility

Cell contractility and migration by integrins depends on precise regulation of protein tyrosine kinase and Rho-family GTPase activities in specific spatiotemporal patterns. Here we show that protein tyrosine phosphatase PTP1B cooperates with β3 integrin to activate the Src/FAK signalling pathway whi...

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Detalles Bibliográficos
Autores principales:	González Wusener, Ana E., González, Ángela, Nakamura, Fumihiko, Arregui, Carlos O.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Company of Biologists Ltd 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4728310/ https://www.ncbi.nlm.nih.gov/pubmed/26700725 http://dx.doi.org/10.1242/bio.015883

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