Regulation of mitochondrial oxidative stress by β-arrestins in cultured human cardiac fibroblasts

Oxidative stress in cardiac fibroblasts (CFs) promotes transformation to myofibroblasts and collagen synthesis leading to myocardial fibrosis, a precursor to heart failure (HF). NADPH oxidase 4 (Nox4) is a major source of cardiac reactive oxygen species (ROS); however, mechanisms of Nox4 regulation...

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Detalles Bibliográficos
Autores principales: Philip, Jennifer L., Razzaque, Md. Abdur, Han, Mei, Li, Jinju, Theccanat, Tiju, Xu, Xianyao, Akhter, Shahab A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4728312/
https://www.ncbi.nlm.nih.gov/pubmed/26449263
http://dx.doi.org/10.1242/dmm.019968

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4728312/
https://www.ncbi.nlm.nih.gov/pubmed/26449263
http://dx.doi.org/10.1242/dmm.019968

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