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CLARITY and PACT-based imaging of adult zebrafish and mouse for whole-animal analysis of infections

Visualization of infection and the associated host response has been challenging in adult vertebrates. Owing to their transparency, zebrafish larvae have been used to directly observe infection in vivo; however, such larvae have not yet developed a functional adaptive immune system. Cells involved i...

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Detalles Bibliográficos
Autores principales: Cronan, Mark R., Rosenberg, Allison F., Oehlers, Stefan H., Saelens, Joseph W., Sisk, Dana M., Jurcic Smith, Kristen L., Lee, Sunhee, Tobin, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4728314/
https://www.ncbi.nlm.nih.gov/pubmed/26449262
http://dx.doi.org/10.1242/dmm.021394