MAP3K1 function is essential for cytoarchitecture of the mouse organ of Corti and survival of auditory hair cells

MAP3K1 is a serine/threonine kinase that is activated by a diverse set of stimuli and exerts its effect through various downstream effecter molecules, including JNK, ERK1/2 and p38. In humans, mutant alleles of MAP3K1 are associated with 46,XY sex reversal. Until recently, the only phenotype observe...

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Detalles Bibliográficos
Autores principales: Yousaf, Rizwan, Meng, Qinghang, Hufnagel, Robert B., Xia, Ying, Puligilla, Chandrakala, Ahmed, Zubair M., Riazuddin, Saima
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4728323/
https://www.ncbi.nlm.nih.gov/pubmed/26496772
http://dx.doi.org/10.1242/dmm.023077

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4728323/
https://www.ncbi.nlm.nih.gov/pubmed/26496772
http://dx.doi.org/10.1242/dmm.023077

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