Loss of arylformamidase with reduced thymidine kinase expression leads to impaired glucose tolerance

Tryptophan metabolites have been linked in observational studies with type 2 diabetes, cognitive disorders, inflammation and immune system regulation. A rate-limiting enzyme in tryptophan conversion is arylformamidase (Afmid), and a double knockout of this gene and thymidine kinase (Tk) has been rep...

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Detalles Bibliográficos
Autores principales: Hugill, Alison J., Stewart, Michelle E., Yon, Marianne A., Probert, Fay, Cox, I. Jane, Hough, Tertius A., Scudamore, Cheryl L., Bentley, Liz, Wall, Gary, Wells, Sara E., Cox, Roger D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4728350/
https://www.ncbi.nlm.nih.gov/pubmed/26432886
http://dx.doi.org/10.1242/bio.013342

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4728350/
https://www.ncbi.nlm.nih.gov/pubmed/26432886
http://dx.doi.org/10.1242/bio.013342

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