metilene: fast and sensitive calling of differentially methylated regions from bisulfite sequencing data

The detection of differentially methylated regions (DMRs) is a necessary prerequisite for characterizing different epigenetic states. We present a novel program, metilene, to identify DMRs within whole-genome and targeted data with unrivaled specificity and sensitivity. A binary segmentation algorit...

Descripción completa

Detalles Bibliográficos
Autores principales: Jühling, Frank, Kretzmer, Helene, Bernhart, Stephan H., Otto, Christian, Stadler, Peter F., Hoffmann, Steve
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4728377/
https://www.ncbi.nlm.nih.gov/pubmed/26631489
http://dx.doi.org/10.1101/gr.196394.115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4728377/
https://www.ncbi.nlm.nih.gov/pubmed/26631489
http://dx.doi.org/10.1101/gr.196394.115

Ejemplares similares