Detecting the Common and Individual Effects of Rare Variants on Quantitative Traits by Using Extreme Phenotype Sampling

Next-generation sequencing technology has made it possible to detect rare genetic variants associated with complex human traits. In recent literature, various methods specifically designed for rare variants are proposed. These tests can be broadly classified into burden and nonburden tests. In this...

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Detalles Bibliográficos
Autores principales: Zhou, Ya-Jing, Wang, Yong, Chen, Li-Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4728382/
https://www.ncbi.nlm.nih.gov/pubmed/26784232
http://dx.doi.org/10.3390/genes7010002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4728382/
https://www.ncbi.nlm.nih.gov/pubmed/26784232
http://dx.doi.org/10.3390/genes7010002

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