Analgesic exposure in pregnant rats affects fetal germ cell development with inter-generational reproductive consequences

Analgesics which affect prostaglandin (PG) pathways are used by most pregnant women. As germ cells (GC) undergo developmental and epigenetic changes in fetal life and are PG targets, we investigated if exposure of pregnant rats to analgesics (indomethacin or acetaminophen) affected GC development an...

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Detalles Bibliográficos
Autores principales: Dean, Afshan, van den Driesche, Sander, Wang, Yili, McKinnell, Chris, Macpherson, Sheila, Eddie, Sharon L., Kinnell, Hazel, Hurtado-Gonzalez, Pablo, Chambers, Tom J., Stevenson, Kerrie, Wolfinger, Elke, Hrabalkova, Lenka, Calarrao, Ana, Bayne, Rosey AL, Hagen, Casper P., Mitchell, Rod T., Anderson, Richard A., Sharpe, Richard M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4728385/
https://www.ncbi.nlm.nih.gov/pubmed/26813099
http://dx.doi.org/10.1038/srep19789

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4728385/
https://www.ncbi.nlm.nih.gov/pubmed/26813099
http://dx.doi.org/10.1038/srep19789

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