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Tcstv1 and Tcstv3 elongate telomeres of mouse ES cells

Mouse embryonic stem cell (ESC) cultures exhibit a heterogeneous mixture of metastable cells sporadically entering the 2-cell (2C)-embryo-like state, critical for ESC potency. One of 2-cell genes, Zscan4, has been shown to be responsible for telomere maintenance, genomic stability and pluripotency o...

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Detalles Bibliográficos
Autores principales: Zhang, Qian, Dan, Jiameng, Wang, Hua, Guo, Renpeng, Mao, Jian, Fu, Haifeng, Wei, Xiawei, Liu, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4728397/
https://www.ncbi.nlm.nih.gov/pubmed/26816107
http://dx.doi.org/10.1038/srep19852