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Generation of 2,000 breast cancer metabolic landscapes reveals a poor prognosis group with active serotonin production

A major roadblock in the effective treatment of cancers is their heterogeneity, whereby multiple molecular landscapes are classified as a single disease. To explore the contribution of cellular metabolism to cancer heterogeneity, we analyse the Metabric dataset, a landmark genomic and transcriptomic...

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Detalles Bibliográficos
Autores principales: Leoncikas, Vytautas, Wu, Huihai, Ward, Lara T., Kierzek, Andrzej M., Plant, Nick J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4728432/
https://www.ncbi.nlm.nih.gov/pubmed/26813959
http://dx.doi.org/10.1038/srep19771