Stepwise B-cell-dependent expansion of T helper clonotypes diversifies the T-cell response

Antigen receptor diversity underpins adaptive immunity by providing the ground for clonal selection of lymphocytes with the appropriate antigen reactivity. Current models attribute T cell clonal selection during the immune response to T-cell receptor (TCR) affinity for either foreign or self peptide...

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Detalles Bibliográficos
Autores principales: Merkenschlager, Julia, Ploquin, Mickaël J., Eksmond, Urszula, Andargachew, Rakieb, Thorborn, Georgina, Filby, Andrew, Pepper, Marion, Evavold, Brian, Kassiotis, George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4728444/
https://www.ncbi.nlm.nih.gov/pubmed/26728651
http://dx.doi.org/10.1038/ncomms10281

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4728444/
https://www.ncbi.nlm.nih.gov/pubmed/26728651
http://dx.doi.org/10.1038/ncomms10281

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