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Stepwise B-cell-dependent expansion of T helper clonotypes diversifies the T-cell response
Antigen receptor diversity underpins adaptive immunity by providing the ground for clonal selection of lymphocytes with the appropriate antigen reactivity. Current models attribute T cell clonal selection during the immune response to T-cell receptor (TCR) affinity for either foreign or self peptide...
Autores principales: | Merkenschlager, Julia, Ploquin, Mickaël J., Eksmond, Urszula, Andargachew, Rakieb, Thorborn, Georgina, Filby, Andrew, Pepper, Marion, Evavold, Brian, Kassiotis, George |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4728444/ https://www.ncbi.nlm.nih.gov/pubmed/26728651 http://dx.doi.org/10.1038/ncomms10281 |
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