Diverse Mechanisms of Sp1-Dependent Transcriptional Regulation Potentially Involved in the Adaptive Response of Cancer Cells to Oxygen-Deficient Conditions

The inside of a tumor often contains a hypoxic area caused by a limited supply of molecular oxygen due to aberrant vasculature. Hypoxia-inducible factors (HIFs) are major transcription factors that are required for cancer cells to adapt to such stress conditions. HIFs, complexed with the aryl hydroc...

Descripción completa

Detalles Bibliográficos
Autores principales: Koizume, Shiro, Miyagi, Yohei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4728449/
https://www.ncbi.nlm.nih.gov/pubmed/26703734
http://dx.doi.org/10.3390/cancers8010002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4728449/
https://www.ncbi.nlm.nih.gov/pubmed/26703734
http://dx.doi.org/10.3390/cancers8010002

Ejemplares similares