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Stress Response Leading to Resistance in Glioblastoma—The Need for Innovative Radiotherapy (iRT) Concepts

Glioblastoma (GBM) is the most common and most aggressive malignant primary brain tumor in adults. In spite of multimodal therapy concepts, consisting of surgery, radiotherapy and chemotherapy, the median survival, merely 15–18 months, is still poor. Mechanisms for resistance of GBM to radio(chemo)t...

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Detalles Bibliográficos
Autores principales: Combs, Stephanie E., Schmid, Thomas E., Vaupel, Peter, Multhoff, Gabriele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4728462/
https://www.ncbi.nlm.nih.gov/pubmed/26771644
http://dx.doi.org/10.3390/cancers8010015