Neuron-derived FGF10 ameliorates cerebral ischemia injury via inhibiting NF-κB-dependent neuroinflammation and activating PI3K/Akt survival signaling pathway in mice

FGF10 is a member of fibroblast growth factors (FGFs). We previously showed that FGF10 protects neuron against oxygen-glucose deprivation injury in vitro; however, the effect of FGF10 in ischemic stroke in vivo is unknown. In the present study, we showed that FGF10 was mainly expressed in neurons bu...

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Detalles Bibliográficos
Autores principales: Li, Yong-Hua, Fu, Hai-Long, Tian, Mou-Li, Wang, Yong-Qiang, Chen, Wei, Cai, Lin-Lin, Zhou, Xu-Hui, Yuan, Hong-Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4728497/
https://www.ncbi.nlm.nih.gov/pubmed/26813160
http://dx.doi.org/10.1038/srep19869

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4728497/
https://www.ncbi.nlm.nih.gov/pubmed/26813160
http://dx.doi.org/10.1038/srep19869

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