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Neuron-derived FGF10 ameliorates cerebral ischemia injury via inhibiting NF-κB-dependent neuroinflammation and activating PI3K/Akt survival signaling pathway in mice
FGF10 is a member of fibroblast growth factors (FGFs). We previously showed that FGF10 protects neuron against oxygen-glucose deprivation injury in vitro; however, the effect of FGF10 in ischemic stroke in vivo is unknown. In the present study, we showed that FGF10 was mainly expressed in neurons bu...
Autores principales: | Li, Yong-Hua, Fu, Hai-Long, Tian, Mou-Li, Wang, Yong-Qiang, Chen, Wei, Cai, Lin-Lin, Zhou, Xu-Hui, Yuan, Hong-Bin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4728497/ https://www.ncbi.nlm.nih.gov/pubmed/26813160 http://dx.doi.org/10.1038/srep19869 |
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