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Exploring Reovirus Plasticity for Improving Its Use as Oncolytic Virus

Reoviruses are non-enveloped viruses with a segmented double stranded RNA genome. In humans, they are not associated with serious disease. Human reoviruses exhibit an inherent preference to replicate in tumor cells, which makes them ideally suited for use in oncolytic virotherapies. Their use as ant...

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Detalles Bibliográficos
Autores principales: Kemp, Vera, Hoeben, Rob C., van den Wollenberg, Diana J. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4728564/
https://www.ncbi.nlm.nih.gov/pubmed/26712782
http://dx.doi.org/10.3390/v8010004