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Exploring Reovirus Plasticity for Improving Its Use as Oncolytic Virus
Reoviruses are non-enveloped viruses with a segmented double stranded RNA genome. In humans, they are not associated with serious disease. Human reoviruses exhibit an inherent preference to replicate in tumor cells, which makes them ideally suited for use in oncolytic virotherapies. Their use as ant...
Autores principales: | Kemp, Vera, Hoeben, Rob C., van den Wollenberg, Diana J. M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4728564/ https://www.ncbi.nlm.nih.gov/pubmed/26712782 http://dx.doi.org/10.3390/v8010004 |
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