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Quantifying Next Generation Sequencing Sample Pre-Processing Bias in HIV-1 Complete Genome Sequencing

Genetic analyses play a central role in infectious disease research. Massively parallelized “mechanical cloning” and sequencing technologies were quickly adopted by HIV researchers in order to broaden the understanding of the clinical importance of minor drug-resistant variants. These efforts have,...

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Detalles Bibliográficos
Autores principales: Vrancken, Bram, Trovão, Nídia Sequeira, Baele, Guy, van Wijngaerden, Eric, Vandamme, Anne-Mieke, van Laethem, Kristel, Lemey, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4728572/
https://www.ncbi.nlm.nih.gov/pubmed/26751471
http://dx.doi.org/10.3390/v8010012